ImmuneWatch DETECT

TCR specificity annotations for comprehensive T-cell response analysis.

Struggling with finding the epitope-specificity of your T-cell receptors?

ImmuneWatch’s DETECT platform uses machine learning to annotate the epitope specificity of T-cell receptor (TCR) sequences.

Speed

Annotate a full TCR repertoire in under 2 minutes on a regular laptop. No GPUs or large computing power required.

Keep your data secure

No need to connect to the cloud. Run ImmuneWatch DETECT on your own infrastructure.

Best-in-class algorithm

ImmuneWatch DETECT obtained the highest classification score in a public benchmark organised by top scientists in the field.

Track >1700 Epitopes with IMWdb

Use the ImmuneWatch database, IMWdb, to track more than 1700 different epitopes. IMWdb is curated by professionals and leads to the best performance of ImmuneWatch DETECT. New epitopes related to viruses, bacteria and cancers are added every month. Alternatively, you can provide your own custom training dataset to find TCRs specific to your epitope of interest.

"Together with ImmuneWatch we were able to assess vaccine-induced T-cell signatures in our unique longitudinal sample collection of cancer patients. Based on antibody titers, it has previously been shown that cancer patients induce a weaker response towards COVID19 vaccines. T-cell immunity in this context is far less characterized and understood. Thanks to the ImmuneWatch DETECT platform we were able to take a deep dive into the SARS-CoV-2-specific T-cell response of our cancer patient cohort. "

Prof. Dr. Eva Lion & Prof. Dr. Timon Vandamme
University of Antwerp - University Hospital Antwerp

ImmuneWatch DETECT wins Machine Learning competition

We are excited to share our recent win in the IMMREP23 Kaggle competition focused on TCR (T-cell receptor) specificity prediction.

Read the article

Our offering

Make your vaccine design process more data-driven by implementing machine learning and approaches from reverse vaccinology.

Reverse vaccinology as a service

Project pricing upon request
Request a quote
Complete reverse vaccinology pipeline
MHC I and MHC II predictions
T-cell immunogenicity
Antigen size filtering
Run local or in the cloud
Unlimited samples

TCR Sequencing Whitepaper

TCR sequencing for cancer vaccine development

To know the efficacy of your cancer vaccine, it is crucial to analyse the T cell response. Because of its versatility, TCR sequencing is a rising tool to monitor such immune responses. However, the full potential of TCR sequencing remains unrealised at present.

This white paper is directed toward researchers and developers of therapeutic cancer vaccines. It offers a brief overview of TCR sequencing and how it has been applied in the field of therapeutic cancer vaccination. Additionally, we highlight common challenges encountered in the data analysis and present examples of how these can be overcome with state-of-the-art data analysis techniques.

Our offering

Find the epitope-specificity of your TCRs today

ImmuneWatch DETECT

FREE for academic researchers, students and non-profit institutes
Request your FREE Licence Key

Best-in-class TCR-epitope prediction algorithm

Support through community forums

Deployment through Docker

Run on 1 device

Unlimited number of samples

ImmuneWatch DETECT Premium

Discounted Enterprise version for
academic researchers, students and non-profit institutes
Request Free 30-day Trial or Quote

Best-in-class TCR-epitope prediction algorithm

Explainability of TCR-epitope predictions

Email support within 5 business days

Installation support

Deployment through Docker, Podman or Singularity

Run on 1 device

Unlimited number of samples

ImmuneWatch DETECT Premium

For Biotech, Pharma, CRO's and TCR sequencing providers
Request Free 30-day Trial or Quote

Best-in-class TCR-epitope prediction algorithm

Explainability of TCR-epitope predictions

Email support within 3 business days

Deployment through Docker, Podman or Singularity

Installation support

Run on 5 devices

6h of immunoinformatic consulting/year included

ImmuneWatch DETECT Service

Discuss your project with our immunoinformatic experts
Request a Quote

In-depth data analysis by immunoinformatic experts

Detect pathogen-, vaccine-, therapy-specific TCRs with our best-in-class TCR-epitope prediction algorithm

Possibility to generate data for your epitopes of interest

FAQ

Find more information and answers to frequently asked questions on our documentation pages.

ImmuneWatch DETECT is an algorithm that falls into the “seen epitope models” category. This means that it needs to have training data on an epitope, before it can detect TCRs related to this epitope. 

IMWdb currently contains more than 1700 epitopes and is continuously expanded. In addition, we offer a service to generate the data specifically for your epitope of interest. Request a quote here.

A true “unseen epitope model” is currently being researched.

No, ImmuneWatch DETECT is able to annotate both the Alpha and Beta chains of TCRs. In addition, it can also work Delta and Gamma chains.

Yes, we can help you out with your TCR sequencing project as well. Feel free to contact us for a quote for your project.

Outre la localisation de vos outils, HeronTrack vous permet de suivre et de planifier vos inspections internes et externes. HeronTrack intègre les rapports de tous les organismes d'inspection externes et propose des formulaires qui peuvent être utilisés pour les inspections internes telles que les outils électriques, les échelles et autres. En outre, les réservations d'outils et les réparations peuvent également être gérées via l'application mobile et web.

Il y a deux groupes d'utilisateurs : ceux qui n'ont accès qu'à l'application mobile, comme les ouvriers et les conducteurs, et ceux qui ont accès à l'application mobile et à l'application web, comme les informaticiens, les responsables d'entrepôt, les chefs de projet, etc.

Find the epitope-specificity of your TCRs today

Contact us to start optimising your vaccine design process today